November 21, 1995Proceedings of the National Academy of SciencesOpen Access

Cloning of a sodium channel alpha subunit from rabbit Schwann cells.

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Population

Cultured Schwann cells from rabbits

Design

Preclinical

Authors

SBScott M. BelcherNorth Carolina State University CZCynthia ZerilloYale University RLRobert LevensonSoka University of America

Discussion

Member takes

Implication

Hypothesis-generating for glial Na channel diversity; extends brain channel data but leaves open human disease relevance.

Structured PICO

Population

Cultured Schwann cells from rabbits

Intervention

Cloning and sequencing of a Na-channel alpha subunit (Nas)

Outcome

Identification and characterization of the Nas alpha subunit sequence and expression pattern

The study identifies a novel sodium channel alpha subunit (Nas) in rabbit Schwann cells that is closely related to brain Na channels and restricted to nervous system tissues.

Cite This Study

Belcher et al. (1995) studied this question.

synapsesocial.com/papers/6a77f3947ecc675f86aebb81 https://doi.org/10.1073/pnas.92.24.11034

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Bookmark

Cloning of a sodium channel alpha subunit from rabbit Schwann cells.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Cloning of a sodium channel alpha subunit from rabbit Schwann cells.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider