Why the study?
It was unknown whether NT-proBNP predicts subsequent MACCE in patients who underwent successful PCI for ACS and had normal LVEF.
Does peak NT-proBNP predict subsequent MACCE in ACS patients with normal LVEF after successful PCI?
Population
3986 ACS patients with successful PCI and normal LVEF
Comparison
Quartiles (Q1-Q4) of peak in-hospital NT-proBNP
Design
Cohort study
Follow-up
Median of 35 months
Authors
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NT-proBNP elevation was associated with higher MACCE risk; supports evaluation for risk stratification in ACS with normal LVEF post-PCI but leaves prospective validation open.
Does peak NT-proBNP predict subsequent MACCE in ACS patients with normal LVEF after successful PCI?
Elevated NT-proBNP during hospitalization independently predicts long-term MACCE and improves risk stratification beyond the TIMI risk score in ACS patients with normal LVEF after successful PCI.
Wang et al. (2020) studied this question.
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