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Highlights the emerging classification of chronic thromboembolic disease (CTED) without pulmonary hypertension and the debate over diagnostic thresholds for PH.
There is renewed interest in the haemodynamic definitions of pulmonary hypertension (PH), reigniting an old debate about diagnostic thresholds [1]. Recent prospective data support work dating back over 40 years demonstrating patients with “borderline” PH (mean pulmonary artery pressure (mPAP) <25 mmHg) can still have significant morbidity and mortality [2]. Therefore, lowering the mPAP threshold for the diagnosis of precapillary pulmonary arterial hypertension (PAH) has been discussed at World Symposium on Pulmonary Hypertension in Nice, France, in 2018. A potentially different approach has arisen in group 4 (chronic thromboembolic pulmonary hypertension (CTEPH)), where the concept of chronic thromboembolic disease without PH (CTED) has gained traction. Chronic thromboembolic disease (CTED) without pulmonary hypertension is emerging as a new and important disease classification <http://ow.ly/ZmK730mv5Xh>
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Swietlik et al. (2018) studied this question.
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