What question did this study set out to answer?

To evaluate the prevalence of metabolic syndrome and its specific components in men with prostate cancer receiving long-term androgen-deprivation therapy.

August 18, 2006Journal of Clinical Oncology

Metabolic Syndrome in Men With Prostate Cancer Undergoing Long-Term Androgen-Deprivation Therapy

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Authors

MBMilena Braga‐BasariaBrigham and Women's Hospital ADAdrian S. DobsJohns Hopkins University DMDenis C. MullerThe University of Melbourne

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Implication

Cross-sectional study reveals increased metabolic syndrome prevalence in prostate cancer patients receiving long-term androgen-deprivation therapy, indicating elevated cardiovascular risk.

Key Points

To evaluate the prevalence of metabolic syndrome and its specific components in men with prostate cancer receiving long-term androgen-deprivation therapy.
Cross-sectional study evaluating 58 age-matched men: 20 with prostate cancer on androgen-deprivation therapy (ADT) for at least 12 months, 18 with locally treated prostate cancer not receiving ADT, and 20 eugonadal controls.
Metabolic syndrome was diagnosed according to the Adult Treatment Panel III criteria, alongside evaluations of body mass index and testosterone levels.
Metabolic syndrome was present in over 50% of men receiving ADT, showing significantly higher prevalence compared to non-ADT patients (P < .01) and healthy controls (P = .03).
Men on ADT had significantly higher rates of abdominal obesity and hyperglycemia, as well as elevated triglycerides compared with controls (P = .02), whereas rates of hypertension and low HDL levels were similar.

Cite This Study

Braga‐Basaria et al. (2006) studied this question.

synapsesocial.com/papers/6a783adbd3a6aa87c6be2f4d https://doi.org/10.1200/jco.2006.05.9741

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Implication

Cross-sectional study reveals increased metabolic syndrome prevalence in prostate cancer patients receiving long-term androgen-deprivation therapy, indicating elevated cardiovascular risk.

Metabolic Syndrome in Men With Prostate Cancer Undergoing Long-Term Androgen-Deprivation Therapy

Discussion

Member takes

Implication

Key Points

Cite This Study

Metabolic Syndrome in Men With Prostate Cancer Undergoing Long-Term Androgen-Deprivation Therapy

Discussion

Member takes

Implication

Key Points

Cite This Study

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