This review summarizes the pathophysiological mechanisms linking HFpEF and type 2 diabetes mellitus, including diabetic cardiomyopathy and potential therapeutic strategies.
The review discusses the relationship between chronic heart failure and diabetes mellitus type 2, metabolic phenotypes of patients w ith chronic heart failure with preserved left ventricular ejection fraction (HFpEF), features of the pathophysiological interaction between diabetes mellitus and HFpEF. Chronic inflammatory condition, metabolic disorders and comorbidities are the pathophysiological basis of HFpEF. The review discusses the concept of diabetic cardiomyopathy, its molecular mechanism and current possibilities of treating this pathology, considering the impact on the prognosis.
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Ларина et al. (2022) studied this question.
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