Population
In vitro platelet-rich plasma, whole blood, apheresed leukocyte-poor platelet units, and a megakaryocytic…
Comparison
Platelet aggregation induced by thrombin… vs Unaggregated plasma
Design
Preclinical
Authors
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Serum VEGF overestimation from platelet release warrants plasma assays; extends mechanistic data but leaves open vascular repair roles in humans.
VEGF is secreted during platelet aggregation, suggesting a constitutive role for platelet VEGF in vascular repair and intimal proliferation at sites of thrombosis.
Maloney et al. (1998) studied this question.
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