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April 26, 2005Hypertension

Hypertension Management in the Elderly Has Improved

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Key result

Between 1994 and 2002, the proportion of elderly patients prescribed multiple concurrent antihypertensives within 2 years of diagnosis increased from 21% to 40% (P<0.0001).

Why the study?

Has the physician management of hypertension in elderly Canadians become more aggressive between 1994 and 2002?

Population

196,451 elderly patients newly started on an antihypertensive agent between July 1, 1994, and March 31…

Comparison

Antihypertensive therapy prescribing patterns in… vs Antihypertensive therapy prescribing patterns in…

Design

Cohort

Follow-up

2 years

Authors

KTKaren TuPreventive CardiologyNCNorman R.C. CampbellPreventive CardiologyMDMinh Duong-HuaCanadian Institute for Health Information

Discussion

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Implication

Suggests shifting practice toward combination regimens in elderly hypertension; leaves open effects on outcomes and safety.

Study Design

Type

Cohort (n=196,451)

Structured PICO

Has the physician management of hypertension in elderly Canadians become more aggressive between 1994 and 2002?

P
Population
196,451 patients aged ≥66 years newly started on antihypertensive therapy between 1994 and 2002, followed for 2 years.
E
Exposure
Antihypertensive therapy prescribing patterns in 2002
C
Comparator
Antihypertensive therapy prescribing patterns in 1994
O
Outcome
Frequency of new prescriptions, frequency of concurrent multiple antihypertensives within 2 years of diagnosis, and discontinuation rates for antihypertensive therapy

Main Result

Absolute Event Rate: 40% vs 21%

p-value: p=<0.0001

Physician management of hypertension in elderly Canadians became significantly more aggressive and persistent between 1994 and 2002.

Cite This Study

Tu et al. (2005) conducted a cohort in Hypertension (n=196,451). Antihypertensive therapy in 2002 vs. Antihypertensive therapy in 1994 was evaluated on Prescription of multiple antihypertensives concurrently within 2 years of diagnosis (p=<0.0001). Between 1994 and 2002, the proportion of elderly patients prescribed multiple concurrent antihypertensives within 2 years of diagnosis increased from 21% to 40% (P<0.0001).

synapsesocial.com/papers/6a78515f7ecc675f86aeec4chttps://doi.org/10.1161/01.hyp.0000164573.01177.95

Topics

Hypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Awareness, Treatment, and Control of Hypertension in Canada1997 · 350 citations
  2. 2Are β-Blockers Efficacious as First-line Therapy for Hypertension in the Elderly?1998 · 561 citations
  3. 3Continuation of initial antihypertensive medication after 1 year of therapy1998 · 299 citations
  4. 4Is it time to move to multidrug combinations?2003 · 26 citations
  5. 5Physician-Related Barriers to the Effective Management of Uncontrolled Hypertension2002 · 487 citations