Answers are grounded in this paper and cite their sources.
Stabilized Wittig olefination holds great potential as a bioconjugation reaction. We demonstrate that the reaction of stabilized phosphorus ylides (or phosphonium salts) with aryl aldehydes is sufficiently robust to be used for live cell affinity isolation and fluorescence tagging of a protein, FKBP12.
No takes yet. Share an insight, caveat, or question.
Lum et al. (2013) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: