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December 2, 2009Proceedings of the National Academy of SciencesOpen Access

Conditional c- myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation

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Authors

YLYen K. LieuColumbia University Irving Medical CenterERE. Premkumar ReddyThe Graduate Center, CUNY

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Lieu et al. (2009) studied this question.

synapsesocial.com/papers/6a785e802e130d02afed1c4dhttps://doi.org/10.1073/pnas.0907623106
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Also Consider

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  1. 1Efficient and Rapid Induction of a Chronic Myelogenous Leukemia-Like Myeloproliferative Disease in Mice Receiving P210 bcr/abl-Transduced Bone Marrow1998 · 742 citations
  2. 2The purification and characterization of fetal liver hematopoietic stem cells.1995 · 623 citations
  3. 3Requirement of c-myb in T cell development and in mature T cell function2004 · 80 citations