Key result
Following the introduction of the rotavirus vaccine in Mozambique, the predominant G9P[8] genotype was significantly reduced, with G3P[8] and G1P[8] emerging as the most common genotypes.
Why the study?
To report the diversity and prevalence of rotavirus genotypes pre- and post-monovalent vaccine introduction in Mozambique.
Does the introduction of the rotavirus monovalent vaccine change the diversity and prevalence of rotavirus genotypes in diarrheic children under five?
Observational
Yes
Does the introduction of the rotavirus monovalent vaccine change the diversity and prevalence of rotavirus genotypes in diarrheic children under five?
The introduction of the rotavirus vaccine in Mozambique was associated with a shift in rotavirus genotype prevalence, highlighting the need for ongoing surveillance.
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Rotavirus genotype surveillance post-vaccine rollout warrants continuation; leaves open effectiveness against emerging strains in Mozambique.
João et al. (2020) conducted an observational in Diarrhea (Rotavirus infection). Rotarix vaccine introduction vs. Pre-vaccine period (2012-2015) was evaluated on Rotavirus genotype prevalence and diversity. Following the introduction of the rotavirus vaccine in Mozambique, the predominant G9P[8] genotype was significantly reduced, with G3P[8] and G1P[8] emerging as the most common genotypes.
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