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December 1, 1995Blood Coagulation & Fibrinolysis

Multicenter evaluation of a new capillary blood prothrombin time monitoring system

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Why the study?

Does the CoaguChek capillary blood prothrombin time monitoring system provide acceptable agreement with standard venous plasma methods in patients on oral anticoagulation?

Population

359 patients under oral anticoagulation therapy with phenprocoumon, acenocoumarin or warfarin

Comparison

CoaguChek capillary blood prothrombin time… vs Citrated venous plasma tested with Hepato Quick…

Design

Other

Authors

ABA M H P van den BesselaarLeiden University Medical CenterKBK. BreddinGoethe University FrankfurtGLG LutzeUniversity Hospital Magdeburg

Discussion

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Member takes

Implication

Supports CoaguChek for decentralized PT monitoring; extends method agreement data while leaving clinical outcome impact open.

Structured PICO

Does the CoaguChek capillary blood prothrombin time monitoring system provide acceptable agreement with standard venous plasma methods in patients on oral anticoagulation?

P
Population
359 patients under oral anticoagulation therapy with phenprocoumon, acenocoumarin or warfarin
I
Intervention
CoaguChek capillary blood prothrombin time monitoring system
C
Comparator
Citrated venous plasma tested with Hepato Quick and Thromborel S
O
Outcome
Agreement of prothrombin time/INR results between CoaguChek and comparison methodssurrogate

The CoaguChek system demonstrates good analytical performance and agreement with standard venous methods, supporting its use for decentralized prothrombin time testing.

Cite This Study

Besselaar et al. (1995) studied this question.

synapsesocial.com/papers/6a7862057ecc675f86aef4aehttps://doi.org/10.1097/00001721-199512000-00005
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparative Study of a Portable Prothrombin Time Monitor Employing Three Different Systems in Oral Anticoagulant Units2001 · 13 citations
  2. 2Reliability of Prothrombin and Activated Partial Thromboplastin Time Determination on CoaguChek Pro DM2004 · 2 citations
  3. 3Reliability of International Normalized Ratio Results in the CoaguChek Pro II System in a Clinical Setting2023 · 2 citations
  4. 4Comparative Study of a Portable Monitor for Prothrombin Time Determination, Coaguchek<sup>®</sup>, with Three Systems for Control of Oral Anticoagulant Treatment1998 · 19 citations
  5. 5Performance of a point-of-care device in determining prothrombin time in an anticoagulation clinic2012 · 8 citations