Why the study?
Is the discrepancy between clinic and ambulatory blood pressure in elderly patients with isolated systolic hypertension associated with plasma renin activity, blood pressure variability, or heart rate?
Population
120 elderly subjects, comprising 81 untreated patients with clinic-defined isolated systolic hypertension…
Comparison
24-hour ambulatory blood pressure monitoring and… vs Normotensive elderly subjects
Design
Cross-sectional
Authors
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Clinic-defined elderly ISH often reflects white-coat effect; cross-sectional data leave mechanisms beyond PRA, HR, and variability unresolved.
Is the discrepancy between clinic and ambulatory blood pressure in elderly patients with isolated systolic hypertension associated with plasma renin activity, blood pressure variability, or heart rate?
A significant proportion of elderly patients with clinic-defined isolated systolic hypertension exhibit 'white coat' hypertension, which is not explained by differences in plasma renin activity, heart rate, or blood pressure variability.
Ruddy et al. (1988) studied this question.
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