Key result
In patients with hypertriglyceridemia-induced acute pancreatitis, there was no statistically significant relationship between BISAP severity scores and triglyceride levels (p=0.569).
Why the study?
Although hypertriglyceridemia is a recognized cause of acute pancreatitis, its clinical course remains unknown, and lipemic serum can interfere with pancreatic enzyme measurements.
Observational (n=30)
No
p-value: p=0.569
In a small retrospective cohort of patients with hypertriglyceridemia-induced acute pancreatitis, there was no significant association between BISAP score and age, gender, habits, or triglyceride levels.
Observational data on hypertriglyceridemia pancreatitis diagnosis remain limited; leaves open need for validated enzyme assays in lipemic samples.
Background and Aim: Although hypertriglyceridemia is a recognized cause of acute pancreatitis, the clinical course remains unknown. Furthermore, lipemic serum can interfere with precise pancreatic enzyme measurements, making it difficult to diagnose acute pancreatitis. The goal was to examine the clinical performance of hypertriglyceridemia acute pancreatitis and the diagnostic utility of pancreatic enzyme serum measurements. Methods: The demographic, clinical, analytical, and radiological data of 30 patients with hypertriglyceridemia acute pancreatitis were reviewed retrospectively. Acute pancreatitis was diagnosed based on clinical, radiological, and/or laparotomical evidence. When all other reasons were ruled out, serum triglyceride levels of more than 500 mg/dl were deemed the cause of acute pancreatitis. Results: 40% of the patients were between the ages of 50 and 59. In 22 patients (73.3%), the most frequent symptoms were vomiting, 8 diarrhea or constipation (26.6%), 8 nausea (26.6%), 5 loss of appetite (16.6%), 5 fever (16.6%), and 4 chills (13.3%). The patients' mean white blood cell count was 13020.54, their mean amylase was 1184.50, their mean inflammatory marker (CRP) was 91.43, and their mean creatinine was 1.08. By investigating the link between BISAP and age, gender, and behaviors Due to the limited sample size and wide dispersion, there was no statistical association despite the hints offered by the research samples. Conclusion: Elevated blood triglyceride levels are linked to a more severe course of pancreatitis. It is important to emphasize the increased incidence of local problems in HTG patients, which increases proportionately and considerably with HTG severity grade.
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Nabki et al. (2022) conducted an observational in Hypertriglyceridemia acute pancreatitis (n=30). Hypertriglyceridemia was evaluated on Relationship between BISAP score and triglyceride levels (p=0.569). In patients with hypertriglyceridemia-induced acute pancreatitis, there was no statistically significant relationship between BISAP severity scores and triglyceride levels (p=0.569).
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