Key result
Prosthetic valve endocarditis was not associated with an increased risk of perioperative composite adverse events compared to native valve endocarditis (OR 1.4; 95% CI 0.6-3.4; P=0.49).
Why the study?
Does cardiac surgery for prosthetic valve endocarditis have comparable outcomes to surgery for native valve endocarditis in patients requiring surgery for endocarditis?
Cohort (n=188)
No
Does cardiac surgery for prosthetic valve endocarditis have comparable outcomes to surgery for native valve endocarditis in patients requiring surgery for endocarditis?
Odds Ratio: 1.4 (95% CI 0.6–3.4)
Absolute Event Rate: 38.1% vs 30.6%
p-value: p=0.49
Cardiac surgery for prosthetic valve endocarditis can be performed with low operative mortality and mid-term survival comparable to native valve endocarditis at experienced centers.
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May support similar perioperative risk management for prosthetic and native valve endocarditis; leaves open confirmation in prospective studies.
Mori et al. (2018) conducted a cohort in Endocarditis (n=188). Prosthetic valve endocarditis vs. Native valve endocarditis was evaluated on Composite events (death, stroke, prolonged intubation, renal failure and sepsis) (OR 1.4, 95% CI 0.6-3.4, p=0.49). Prosthetic valve endocarditis was not associated with an increased risk of perioperative composite adverse events compared to native valve endocarditis (OR 1.4; 95% CI 0.6-3.4; P=0.49).
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