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August 1, 2026American Journal of Preventive CardiologyOpen Access

Prevalence and Trends of Risk Factors and Comorbidities Among Patients Treated for Acute Myocardial Infarction: Insights from the Hungarian Myocardial Infarction Registry, 2014–2024

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Key result

Smoking, obesity, and diabetes rates rise significantly over 10 years among patients with acute MI.

  • OR 1.11-1.37 for diabetes, OR 1.43-2.08 for smoking, OR 1.37-1.62 for obesity per 10 years
  • n=135,865

Why the study?

The study was conducted to examine the age distribution, common risk factors, and comorbidities among patients with acute myocardial infarction recorded in the Hungarian Myocardial Infarction Registry between 2014 and 2024.

What are the prevalence and trends of risk factors and comorbidities among patients treated for acute myocardial infarction in Hungary between 2014 and 2024?

Population

135,865 patients treated for AMI in Hungary

Design

Mandatory nationwide registry study

Authors

AJAndrás JánosiGottsegen National Cardiovascular CenterZJZoltán JáraiSemmelweis UniversityBMBettina MartusCorvinus University of Budapest

Discussion

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Implication

Hungarian AMI registry data characterize evolving patient profiles; leaves open whether prevention priorities require updating.

Key Points

  • To examine trends in age distribution, common cardiovascular risk factors, and comorbidities among patients treated for acute myocardial infarction over a 10-year period.
  • Analyzed nationwide mandatory registry data from 135,865 patients (39.6% women; 46.6% STEMI) treated for acute myocardial infarction in Hungary between 2014 and 2024.
  • Used generalized additive models with age-adjustment to estimate prevalence time trends and UpSet plots to identify common comorbidity combinations.
  • Hypertension was the most prevalent comorbidity overall, though its observed temporal changes were not clinically relevant.
  • The 10-year odds increased across both sexes and infarction types for diabetes (OR 1.11 to 1.37), obesity (OR 1.37 to 1.62), and smoking (OR 1.43 to 2.08).
  • Hyperlipidemia increased significantly only in STEMI cases, while the proportion of patients older than 80 years decreased significantly in nearly all subgroups.

Study Design

Type

Observational (n=135,865)

Multicenter

Yes

Structured PICO

What are the prevalence and trends of risk factors and comorbidities among patients treated for acute myocardial infarction in Hungary between 2014 and 2024?

P
Population
135,865 patients (39.6% women) treated for acute myocardial infarction in Hungary between 2014 and 2024.
O
Outcome
Prevalence and trends of risk factors and comorbidities (including age distribution, smoking, obesity, diabetes, hypertension, and hyperlipidaemia)

Main Result

Effect estimate: OR 1.11-1.37 for diabetes, OR 1.43-2.08 for smoking, OR 1.37-1.62 for obesity per 10 years

There has been a significant increase in the prevalence of smoking, obesity, and diabetes among patients presenting with acute myocardial infarction in Hungary over the past decade.

Cite This Study

Jánosi et al. (2026) conducted an observational in Acute myocardial infarction (AMI) (n=135,865). Time period (2014-2024) was evaluated on Prevalence of risk factors and comorbidities (OR 1.11-1.37 for diabetes, OR 1.43-2.08 for smoking, OR 1.37-1.62 for obesity per 10 years). Over a 10-year period, the prevalence of smoking (OR 1.43-2.08), obesity (OR 1.37-1.62), and diabetes (OR 1.11-1.37) significantly increased among patients with acute myocardial infarction.

synapsesocial.com/papers/6a7872b0d2fa2470761f76e0https://doi.org/10.1016/j.ajpc.2026.101789
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Does Gender Have Prognostic Value Among Patients with Myocardial Infarction? Analysis of the Data from the Hungarian Myocardial Infarction Registry2018 · 8 citations
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