Key result
Higher brachial-ankle pulse wave velocity was significantly associated with left ventricular remodeling and demonstrated fair discriminant ability for predicting diastolic dysfunction (AUC 0.734).
Why the study?
The usefulness of brachial-ankle pulse wave velocity as an initial screening test for hypertensive patients was not well-known.
Does brachial-ankle pulse wave velocity correlate with left ventricular geometry and diastolic function in untreated hypertensive patients?
Cross-Sectional (n=202)
No
Does brachial-ankle pulse wave velocity correlate with left ventricular geometry and diastolic function in untreated hypertensive patients?
Effect estimate: AUC 0.734 (95% CI 0.648-0.800)
p-value: p=<0.001
Brachial-ankle pulse wave velocity is significantly associated with adverse left ventricular remodeling and diastolic dysfunction in untreated hypertensive patients, suggesting its utility as an early screening tool.
No takes yet. Share an insight, caveat, or question.
baPWV may flag LV remodeling and diastolic issues in untreated hypertension; hypothesis-generating, needs prospective validation before screening use.
Kwak et al. (2021) conducted a cross-sectional in Untreated hypertension (n=202). Brachial-ankle pulse wave velocity (baPWV) was evaluated on Discriminant ability of baPWV in predicting diastolic dysfunction (AUC 0.734, 95% CI 0.648-0.800, p=<0.001). Higher brachial-ankle pulse wave velocity was significantly associated with left ventricular remodeling and demonstrated fair discriminant ability for predicting diastolic dysfunction (AUC 0.734).
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