Key result
Circulating vaccine-derived poliovirus (cVDPV) outbreaks have occurred in multiple countries with poor oral polio vaccine coverage, posing a threat to the global eradication programme.
The emergence of circulating vaccine-derived poliovirus from oral polio vaccines highlights the need for alternative strategies, such as the inactivated polio vaccine, in the final stages of global eradication.
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cVDPV outbreaks signal OPV risks in low-coverage areas; leaves open optimal IPV transition strategies for eradication.
Davis et al. (2013) conducted a review in Circulating vaccine derived poliovirus (cVDPV). Oral polio vaccine (OPV) was evaluated. Circulating vaccine-derived poliovirus (cVDPV) outbreaks have occurred in multiple countries with poor oral polio vaccine coverage, posing a threat to the global eradication programme.
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