Key result
A 40 mmol/L increase in urinary sodium concentration was independently and inversely associated with carotid (-1.38 ± 0.66%; P=0.04) and aortic (-1.54 ± 0.72%; P=0.02) augmentation indexes.
Why the study?
Is urinary sodium associated with central arterial stiffness in a general population?
Observational (n=630)
Is urinary sodium associated with central arterial stiffness in a general population?
Effect estimate: -1.38 ± 0.66% (carotid) and -1.54 ± 0.72% (aortic) per 40 mmol/L increase
p-value: p=0.04 (carotid), 0.02 (aortic)
Higher urinary sodium concentration is inversely associated with central arterial augmentation indexes, suggesting a complex relationship between salt handling and arterial stiffness.
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Higher urinary sodium linked to lower augmentation indexes in this cohort; leaves open causal effects on arterial stiffness and warrants prospective trials.
Liu et al. (2012) reported an observational. Urinary sodium concentration was evaluated on Carotid and aortic augmentation indexes (AIs) (-1.38 ± 0.66% (carotid) and -1.54 ± 0.72% (aortic) per 40 mmol/L increase, p=0.04 (carotid), 0.02 (aortic)). A 40 mmol/L increase in urinary sodium concentration was independently and inversely associated with carotid (-1.38 ± 0.66%; P=0.04) and aortic (-1.54 ± 0.72%; P=0.02) augmentation indexes.
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