Key result
The combination of late diastolic annular velocity > 7.6 cm/s and E'/A' < 1 identified pseudonormal mitral inflow with a sensitivity of 90% and a specificity of 88% in dogs.
Why the study?
Does the combination of Doppler tissue echocardiography and conventional Doppler indices improve the detection of diastolic dysfunction in dogs?
Cross-Sectional (n=31)
Does the combination of Doppler tissue echocardiography and conventional Doppler indices improve the detection of diastolic dysfunction in dogs?
Effect estimate: AUC 0.944
p-value: p=0.002
The combination of Doppler tissue echocardiography of the mitral septal annulus and conventional Doppler indices provides a reliable method for detecting pseudonormal mitral inflow and assessing diastolic dysfunction in dogs.
May aid diastolic assessment in canine models; leaves open translation to veterinary practice pending validation.
The aim of this study was to explore the feasibility and the diagnostic value of conventional Doppler parameters of transmitral inflows and Doppler tissue echocardiography parameters of septal annulus motion for the assessment of diastolic dysfunction in dogs with cardiac failure. The LV diastolic mitral flow patterns were divided into normal diastolic flow pattern (group 1), delayed relaxation pattern (group 2), pseudonormal flow pattern (group 3), and restrictive pattern (group 4). In our study population, 17 patients had normal mitral inflow variables (E/A ratio > 1 and Dt < 109 m). The other 7 patients were classified as having abnormal mitral inflow pattern (E' > 8 cm/s, E'/A' > 1). In conclusion, the combination of Doppler tissue echocardiography of the mitral septal annulus and mitral inflow patterns by conventional Doppler indices provides better estimates of diastolic dysfunction in dogs.
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Kibar et al. (2009) conducted a cross-sectional in Cardiac failure and diastolic dysfunction (in dogs) (n=31). Doppler tissue echocardiography (DTE) and conventional Doppler was evaluated on Identification of pseudonormal (PN) mitral inflow pattern using late diastolic annular velocity (A') (AUC 0.944, p=0.002). The combination of late diastolic annular velocity > 7.6 cm/s and E'/A' < 1 identified pseudonormal mitral inflow with a sensitivity of 90% and a specificity of 88% in dogs.
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