Key result
Doppler-derived -dP/dt and early diastolic peak velocity predict CHF in dogs with chronic mitral valve disease.
Why the study?
Do Doppler-derived dP/dt and -dP/dt predict the risk of heart failure in dogs with chronic mitral valve disease?
Observational
Do Doppler-derived dP/dt and -dP/dt predict the risk of heart failure in dogs with chronic mitral valve disease?
Doppler-derived dP/dt and -dP/dt, combined with conventional echocardiography, can independently predict the risk of congestive heart failure in dogs with chronic mitral valve disease.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for Doppler risk stratification in canine mitral valve disease; leaves open prospective validation and human translation.
than in those of the other classes, whereas values of -dP/dt decreased significantly with the severity of congestive heart failure. The peak velocity of the early diastolic wave and -dP/dt were identified as independent predictors of congestive heart failure. Our findings suggested that Doppler-derived dP/dt and -dP/dt, used in combination with conventional echocardiographic variables, could allow a better understanding of myocardial dysfunction and a possibility for prediction of the risk of heart failure in dogs with chronic mitral valve disease.
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Kim et al. (2018) conducted an observational in Chronic mitral valve disease and congestive heart failure in dogs. Doppler-derived dP/dt and -dP/dt was evaluated on Prediction of congestive heart failure. Doppler-derived -dP/dt and peak velocity of the early diastolic wave were identified as independent predictors of congestive heart failure in dogs with chronic mitral valve disease.
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