Key result
Doppler-derived dP/dt strongly correlates with invasive catheter measurements in dogs with MR.
Why the study?
Does transthoracic continuous-wave Doppler echocardiography accurately estimate cardiac systolic function compared to invasive catheter measurement in dogs with experimental mitral regurgitation?
Population
7 mongrel dogs with experimental mitral regurgitation
Comparison
Transthoracic continuous-wave Doppler… vs Invasive measurement using a…
Design
Preclinical
Authors
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Supports noninvasive dP/dt estimation in canine mitral regurgitation; leaves open clinical translation pending prospective validation.
Does transthoracic continuous-wave Doppler echocardiography accurately estimate cardiac systolic function compared to invasive catheter measurement in dogs with experimental mitral regurgitation?
Effect estimate: r = 0.90
p-value: p=< 0.0001
Transthoracic continuous-wave Doppler echocardiography provides a feasible and accurate noninvasive estimation of cardiac systolic function (dP/dt) in a canine model of mitral regurgitation.
Asano et al. (2002) studied Experimental mitral regurgitation (n=7). Transthoracic continuous-wave Doppler echocardiography vs. Catheter-measured peak dP/dt was evaluated on Correlation of peak rate of left ventricular pressure rise (peak dP/dt) (r = 0.90, p=< 0.0001). Transthoracic continuous-wave Doppler echocardiography-derived dP/dt significantly correlated with catheter-measured peak dP/dt (r = 0.90, P < 0.0001) in dogs with mitral regurgitation.
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