Key result
Acute kidney injury in patients with acute decompensated heart failure was associated with significantly higher in-hospital mortality compared to those without AKI (10.5% vs 1.0%, P=0.0010).
Why the study?
Does acute kidney injury evaluated by the RIFLE criteria predict poorer outcomes in patients with acute decompensated heart failure?
Population
376 consecutive patients with acute decompensated heart failure admitted to the intensive care unit, mean…
Comparison
Acute kidney injury evaluated using the RIFLE… vs Patients without AKI
Design
Cohort
Follow-up
In-hospital
Authors
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AKI by RIFLE criteria flags higher mortality risk in ADHF; hypothesis-generating and requires prospective validation before guiding interventions.
Observational (n=376)
Does acute kidney injury evaluated by the RIFLE criteria predict poorer outcomes in patients with acute decompensated heart failure?
Absolute Event Rate: 10.5% vs 1%
p-value: p=0.0010
Acute kidney injury, as defined by the RIFLE criteria, is associated with significantly higher in-hospital mortality and longer ICU/hospital stays in patients with acute decompensated heart failure.
Hata et al. (2009) conducted an observational in acute decompensated heart failure (n=376). Acute kidney injury (AKI) vs. No AKI was evaluated on in-hospital mortality (p=0.0010). Acute kidney injury in patients with acute decompensated heart failure was associated with significantly higher in-hospital mortality compared to those without AKI (10.5% vs 1.0%, P=0.0010).
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