Key result
Endoglin plays a crucial role in myocardial fibrosis across different models of heart failure, suggesting that targeting endoglin may serve as a novel therapeutic strategy to prevent fibrosis.
Targeting endoglin may provide a novel therapeutic approach for reducing myocardial fibrosis in patients with heart failure.
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Endoglin may be a viable antifibrotic target in heart failure; leaves open clinical efficacy pending prospective trials.
Kou‐Gi Shyu (2017) conducted a review in Myocardial fibrosis and heart failure. Endoglin targeting was evaluated. Endoglin plays a crucial role in myocardial fibrosis across different models of heart failure, suggesting that targeting endoglin may serve as a novel therapeutic strategy to prevent fibrosis.
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