Why the study?
Does insulin-dependent diabetes mellitus (IDDM) reduce heart rate variability in children and adolescents compared to healthy controls?
Population
238 children and adolescents, comprising 130 subjects with insulin-dependent diabetes mellitus and 108…
Design
Case-control
Authors
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IDDM-associated HRV reduction signals early autonomic dysfunction in youth; hypothesis-generating and requires prospective validation before clinical adoption.
Does insulin-dependent diabetes mellitus (IDDM) reduce heart rate variability in children and adolescents compared to healthy controls?
Children and adolescents with IDDM show early autonomic dysfunction characterized by reduced heart rate variability, though power spectral analysis is no more sensitive than other standard HRV measures.
Wawryk et al. (1997) studied this question.
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