Why the study?
Are cardiovascular reflex abnormalities more prevalent in children with IDDM compared to healthy controls?
Population
Ambulatory children with and without IDDM between 6-19 yr of age (n=248 IDDM, n=60 controls).
Comparison
Measurement of heart-rate responses to deep… vs Children without IDDM (healthy controls)
Design
Cross-sectional
Follow-up
1 yr (for a subgroup)
Authors
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May indicate higher autonomic dysfunction prevalence in pediatric IDDM; leaves open whether screening improves outcomes.
Are cardiovascular reflex abnormalities more prevalent in children with IDDM compared to healthy controls?
Simple tests of heart-rate responses to deep breathing and standing can detect cardiovascular reflex abnormalities in nearly a third of children with IDDM.
Ringel et al. (1993) studied this question.
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