Key result
Newly diagnosed type 2 diabetes was associated with a hypercoagulable state, with 38% of patients showing hyperactive platelets and 36% showing raised factor VIII coagulant activity.
Why the study?
Does control of hyperglycaemia improve haemostatic variables in newly diagnosed type 2 diabetic patients?
Observational (n=37)
Does control of hyperglycaemia improve haemostatic variables in newly diagnosed type 2 diabetic patients?
Newly diagnosed type 2 diabetes is associated with a hypercoagulable state that improves with glycemic control, independent of overt vascular disease.
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New T2DM-associated hypercoagulability may warrant vigilance; leaves open whether glycemic control improves haemostatic variables.
Hughes et al. (2009) conducted an observational in Type 2 diabetes (n=37). Control of hyperglycaemia vs. Baseline (at diagnosis) was evaluated on Abnormalities of coagulation, fibrinolysis and platelet behaviour. Newly diagnosed type 2 diabetes was associated with a hypercoagulable state, with 38% of patients showing hyperactive platelets and 36% showing raised factor VIII coagulant activity.
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