Population
Rat left ventricle (whole heart preparation using cross-circulation method)
Comparison
Intracoronary calcium vs Baseline (without intracoronary calcium)
Design
Preclinical
Authors
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Supports PVA and VO2 intercept as valid indices in rat models; leaves open translation to clinical mechanoenergetics.
The study demonstrates that despite a curved end-systolic pressure-volume relation in rats, the VO2-PVA relation remains linear, making PVA and the VO2 intercept valid mechanoenergetic indices in this model.
Hata et al. (1998) studied this question.
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