Key result
Acute schizophrenia was associated with a reduction in baroreflex sensitivity, accompanied by tachycardia and greatly increased left ventricular work index compared to healthy volunteers.
Why the study?
Is acute schizophrenia associated with altered baroreflex sensitivity and cardiovascular regulation compared to healthy volunteers?
Case-Control (n=42)
Is acute schizophrenia associated with altered baroreflex sensitivity and cardiovascular regulation compared to healthy volunteers?
Acute schizophrenia is associated with decreased baroreflex sensitivity and parasympathetic modulation, reflecting dysfunctional cardiovascular regulation that may increase the risk for cardiovascular mortality.
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Signals potential CV risk elevation in acute schizophrenia; observational data leave open causal links to mortality.
Bär et al. (2006) conducted a case-control in Acute schizophrenia (n=42). Acute schizophrenia vs. Healthy volunteers was evaluated on Baroreflex sensitivity. Acute schizophrenia was associated with a reduction in baroreflex sensitivity, accompanied by tachycardia and greatly increased left ventricular work index compared to healthy volunteers.
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