Key result
Overweight/obese African-American adolescents had 7% higher aortic stiffness (CF-PWV) and 3.5% lower pulse-pressure amplification compared to normal-weight peers (all P<0.05).
Why the study?
Does overweight/obesity increase arterial stiffness and alter pulse-pressure amplification in healthy African-American adolescents?
Cross-Sectional (n=227)
Does overweight/obesity increase arterial stiffness and alter pulse-pressure amplification in healthy African-American adolescents?
p-value: p=<0.05
Overweight and obesity in African-American adolescents are associated with higher aortic stiffness and smaller pulse-pressure amplification, which may contribute to increased cardiovascular risk.
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May heighten long-term CV risk in this group; leaves open reversibility with weight loss.
Pierce et al. (2012) conducted a cross-sectional in Obesity (n=227). Overweight/Obesity (BMI ≥ 85th percentile) vs. Normal-weight (BMI < 85th percentile) was evaluated on Arterial stiffness (CF-PWV, CR-PWV) and pulse-pressure amplification (p=<0.05). Overweight/obese African-American adolescents had 7% higher aortic stiffness (CF-PWV) and 3.5% lower pulse-pressure amplification compared to normal-weight peers (all P<0.05).
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