This case report describes a rare primary cardiac synovial sarcoma with a specific (X;18) translocation and suggests a possible association with asbestos exposure.
Supports possible asbestos link in cardiac synovial sarcoma; leaves open causal role from single case report.
A primary cardiac spindle cell tumor with immunoreactivity for keratin proteins is reported. Cytogenetic analysis of the tumor demonstrated a translocation (X;18), an aberration almost exclusively reported in synovial sarcomas. Postmortem examination revealed amphibole asbestos within the lungs and diaphragmatic pleural plaques indicative of asbestos exposure. These findings raise questions about the possible causation of this tumor.
No takes yet. Share an insight, caveat, or question.
Karn et al. (1994) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: