Population
A biphasic synovial sarcoma case with an apparently normal karyotype on initial cytogenetic analysis
Comparison
FISH using chromosome X- and 18-specific probes… vs Initial cytogenetic analysis (karyotyping)
Design
Case_report
Authors
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May miss cryptic t(X;18) by karyotyping alone in soft tissue tumors; leaves open whether routine FISH/RT-PCR improves diagnosis.
Standard RT-PCR and/or FISH analyses should be carried out in soft tissue tumors to reveal masked translocations relevant to diagnosis and prognosis.
Kessel et al. (1998) studied this question.
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