October 1, 2010Vascular Medicine
Fibrinolysis for acute pulmonary embolism
Key result
Fibrinolysis for acute pulmonary embolism is considered life-saving in massive cases but remains controversial for submassive cases due to the risk of major bleeding.
Why the study?
Does fibrinolysis improve outcomes in patients with acute pulmonary embolism?
Population
Patients with acute pulmonary embolism, including massive and submassive presentations
Design
Review
Authors
Discussion
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Member takes
Implication
Supports selective fibrinolysis in massive PE; leaves open its net benefit in submassive cases pending randomized trials.
Structured PICO
Does fibrinolysis improve outcomes in patients with acute pulmonary embolism?
P
Population
Patients with acute pulmonary embolism, including massive and submassive presentations
I
Intervention
Fibrinolysis
Fibrinolysis is considered life-saving for massive PE but remains controversial for submassive PE due to the risk of major bleeding, particularly intracranial hemorrhage.
Cite This Study
Piazza et al. (2010) conducted a review in Acute pulmonary embolism. Fibrinolysis was evaluated. Fibrinolysis for acute pulmonary embolism is considered life-saving in massive cases but remains controversial for submassive cases due to the risk of major bleeding.