Population
Patients with life-threatening pulmonary embolism
Design
Review
Authors
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Limits thrombolysis to high-risk PE with shock; leaves open optimal strategies for intermediate-risk cases.
Thrombolytic therapy is recommended for high-risk PE with hemodynamic instability, while intermediate-risk patients should receive standard anticoagulation with rescue fibrinolysis if deterioration occurs.
Marshall et al. (2015) studied this question.
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