Why the study?
High-risk acute pulmonary embolism carries unacceptably high morbidity and mortality, but treatment approaches vary widely due to a lack of prospective randomized studies, highlighting the need for a standardized approach.
Population
Patients with high-risk acute pulmonary embolism (acute PE associated with hemodynamic instability)
Design
Review
Authors
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May warrant PERT adoption in high-risk PE; leaves open optimal advanced therapy protocols in trials.
The management of hemodynamically unstable acute pulmonary embolism requires a standardized, multidisciplinary approach utilizing PE response teams and advanced therapies to address high mortality rates.
Fulton et al. (2023) studied this question.
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