Key result
Aggressive management of conventional and nonconventional cardiovascular risk factors is necessary to address the high cardiovascular morbidity and mortality in patients with chronic kidney disease.
Aggressive management of cardiovascular risk factors is required in patients with chronic kidney disease (Cardiorenal syndrome type 4) due to persistently high cardiovascular morbidity and mortality.
Urges comprehensive risk factor control in CKD; extends prior reviews on cardiorenal syndrome yet leaves optimal nonconventional strategies open for trials.
Cardiorenal syndrome (CRS) type 4, or chronic renocardiac syndrome, has been defined as 'chronic abnormalities in renal function leading to cardiac disease' and recognizes the extreme burden of cardiovascular (CV) disease (CVD) risk in patients with chronic kidney disease (CKD). CKD is common and increasingly recognized as a risk factor for CVD. Although during the past 10 years CV morbidity and mortality have decreased markedly in the general population, their rates still remain high among CKD patients. For this reason, CKD patients should be evaluated thoroughly for CV risk factors which require an aggressive management, given the significant implications of CRS type 4 at both individual and societal level. We will review the management of the most important conventional and nonconventional CVD risk factors related to CKD.
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Clementi et al. (2013) conducted a review in Cardiorenal Syndrome Type 4. Management of cardiovascular risk factors was evaluated. Aggressive management of conventional and nonconventional cardiovascular risk factors is necessary to address the high cardiovascular morbidity and mortality in patients with chronic kidney disease.
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