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“There is a lot of debate and controversy about how we best define type 4a MIs, with previous studies like EXCEL and ISCHEMIA using their own definitions. Depending on the definition used, this can change the outcomes of these trials quite significantly.”
“This is another example of a nonfatal event that is defined by physicians and measured by physicians but has no effect on patient quality of life [or] well-being. It's an event that is of interest to physicians, but it's not of interest to patients.”
“Although PMI may be regarded an inevitable complication in some patients, and its prognostic significance continues to be debated, it is reassuring to know that there appear to be no long-term adverse consequences in terms of QoL in a population with an otherwise low event rate.”
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Donald E. Cutlip (2020) studied this question.
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