Key result
Meeting ≥2 discharge criteria (fluid reduction >1.3L, sodium >135, NT-proBNP reduction >23%) was associated with lower 30-day heart failure readmission (OR 0.10; 95% CI 0.01-0.68; P=0.019).
Why the study?
Does meeting specific discharge criteria (fluid reduction, normal sodium, NT-proBNP reduction) predict lower 30-day readmission in patients hospitalized with decompensated heart failure?
Cohort (n=412)
Does meeting specific discharge criteria (fluid reduction, normal sodium, NT-proBNP reduction) predict lower 30-day readmission in patients hospitalized with decompensated heart failure?
Odds Ratio: 0.1 (95% CI 0.01–0.68)
p-value: p=0.019
Achieving a negative fluid balance, normal serum sodium, and a reduction in NT-proBNP during hospitalization for decompensated heart failure identifies patients at very low risk for 30-day readmission.
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May aid risk stratification at HF discharge; hypothesis-generating and requires prospective validation before guiding practice.
Hernandez et al. (2013) conducted a cohort in Decompensated Heart Failure (n=412). Meeting ≥2 discharge criteria (fluid reduction >1.3 L, sodium >135, NT-proBNP reduction >23%) vs. Failing to meet ≥2 criteria was evaluated on Heart failure readmission by 30 days (OR 0.10, 95% CI 0.01-0.68, p=0.019). Meeting ≥2 discharge criteria (fluid reduction >1.3L, sodium >135, NT-proBNP reduction >23%) was associated with lower 30-day heart failure readmission (OR 0.10; 95% CI 0.01-0.68; P=0.019).
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