Key result
CRP and procalcitonin yielded sensitivities of 72.82% and 57.28% and specificities of 25% and 41.67% for diagnosing acute appendicitis, indicating they should only be used as adjuncts.
Why the study?
Acute appendicitis is a prevalent abdominal emergency where diagnostic delays increase morbidity and costs, prompting evaluation of CRP and PCT as diagnostic aids.
Does the measurement of CRP and procalcitonin improve the diagnosis of acute appendicitis in patients presenting with right iliac fossa pain?
Population
115 patients aged > 18 years tentatively diagnosed with acute appendicitis undergoing surgery
Comparison
CRP and PCT correlation with perioperative findings
Design
Hospital-based screening test study
Authors
Loading...
Low specificity precludes standalone use in right iliac fossa pain; leaves open adjunctive role pending prospective validation.
Observational (n=115)
Does the measurement of CRP and procalcitonin improve the diagnosis of acute appendicitis in patients presenting with right iliac fossa pain?
Elevation in CRP and procalcitonin levels have low specificity and cannot be used alone for the final diagnosis of acute appendicitis, but may serve as adjuncts.
Khanage et al. (2022) conducted an observational in Acute appendicitis (n=115). CRP and Procalcitonin was evaluated on Diagnostic accuracy for acute appendicitis. CRP and procalcitonin yielded sensitivities of 72.82% and 57.28% and specificities of 25% and 41.67% for diagnosing acute appendicitis, indicating they should only be used as adjuncts.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: