Why the study?
Does pre-operative serum CRP measurement accurately diagnose acute appendicitis in children?
Population
192 children undergoing appendectomy for suspected acute appendicitis
Comparison
Pre-operative measurement of serum C-reactive… vs Histopathology
Design
Cohort, double blind
Authors
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CRP unreliable for ruling in/out pediatric appendicitis preoperatively; leaves open need for validated noninvasive diagnostics in children.
Does pre-operative serum CRP measurement accurately diagnose acute appendicitis in children?
Pre-operative serum CRP measurement is not a reliable tool for diagnosing acute appendicitis in children due to low specificity and negative predictive value.
Amalesh et al. (2004) studied this question.
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