Key result
Preoperative C-reactive protein level is an independent marker for necrotic appendicitis requiring surgery (RR 1.442), with an optimal cutoff value of 4.95 mg/dl.
Why the study?
Does preoperative C-reactive protein level predict the histological severity of acute appendicitis to guide surgical indication?
Population
150 patients who underwent surgical treatment for acute appendicitis in Wakayama Medical University…
Design
Cohort
Authors
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May support CRP for appendicitis severity assessment; leaves open need for prospective validation before guiding surgery.
Observational (n=150)
No
Does preoperative C-reactive protein level predict the histological severity of acute appendicitis to guide surgical indication?
Relative Risk: 1.442 (95% CI 1.242–1.673)
p-value: p=< 0.0001
Preoperative CRP level is an independent marker for predicting the severity of acute appendicitis, with a cutoff of 4.95 mg/dl indicating the need for surgical intervention.
Yokoyama et al. (2009) conducted an observational in Acute appendicitis (n=150). C-reactive protein (CRP) level was evaluated on Necrotic (gangrenous) appendicitis requiring surgical treatment (RR 1.442, 95% CI 1.242-1.673, p=< 0.0001). Preoperative C-reactive protein level is an independent marker for necrotic appendicitis requiring surgery (RR 1.442), with an optimal cutoff value of 4.95 mg/dl.
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