Double-Carbapenem Therapy Not Proven To Be More Active than Carbapenem Monotherapy against KPC-Positive Klebsiella pneumoniae

Hopes of a new option for therapy of KPC-associated infections may have been raised by the report of Bulik and Nicolau that double-carbapenem therapy comprising ertapenem and doripenem can be more active than either drug alone ([3][1]). While not discounting the possibility that carbapenem