Population
64 males, 40-60 years old, comprising 31 patients with previous myocardial infarction and 33 controls.
Design
Case-control
Authors
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C4-MI association is hypothesis-generating; does not support clinical testing or causal inference in coronary disease.
Serum C4 levels are independently associated with previous myocardial infarction, suggesting a link between complement activation and coronary disease.
Muscari et al. (2008) studied this question.
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