Key result
Increased serum fibrin degradation products (FDP) were significantly associated with recurrent myocardial infarction within three months (present in 6 of 7 patients with reinfarction vs 6 of 24 without, p<0.01).
Why the study?
Do levels of plasma fibrinogen, soluble fibrin monomer complexes (FMM), or fibrin degradation products (FDP) predict recurrent MI in patients with acute MI?
Observational (n=31)
Do levels of plasma fibrinogen, soluble fibrin monomer complexes (FMM), or fibrin degradation products (FDP) predict recurrent MI in patients with acute MI?
p-value: p=<0.01
Elevated serum fibrin degradation products (FDP) during hospitalization for acute MI may be associated with an increased risk of recurrent MI within three months.
Elevated FDP may signal higher short-term reinfarction risk after acute MI; leaves open its value as a prognostic marker pending prospective validation.
Plasma fibrinogen, soluble fibrin monomer complexes (FMM) in plasma and fibrin degradation products (FDP) in serum were studied in 31 patients with acute myocardial infarction (MI) during their stay in hospital. The ECGs of 15 patients indicated a high risk of recurrent MI. Seven patients had a recurrent MI within three months. No correlation could be found between plasma fibrinogen or FMM and reinfarction, but FDP was increased in six of the seven patients with reinfarction compared to six of the 24 without (p less than 0.01).
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Rurik Löfmark (1982) conducted an observational in Acute myocardial infarction (MI) (n=31). Plasma fibrinogen, soluble fibrin monomer complexes (FMM), and fibrin degradation products (FDP) was evaluated on Recurrent myocardial infarction (p=<0.01). Increased serum fibrin degradation products (FDP) were significantly associated with recurrent myocardial infarction within three months (present in 6 of 7 patients with reinfarction vs 6 of 24 without, p<0.01).
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