Population
20 pigeons anesthetized with urethane, artificially ventilated, and immobilized, yielding data on 83…
Comparison
Iontophoretic applications of catecholamines and… vs Control and co-application of antagonists
Design
Preclinical
Authors
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Alpha2 receptors mediate clonidine inhibition of sympathetic preganglionic firing in animals; leaves open translation to human cardiovascular therapies.
Catecholamines and clonidine inhibit sympathetic preganglionic neurons via an alpha2-adrenergic receptor mechanism.
Guyenet et al. (1981) studied this question.
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