Hyperbaric hyperoxia reduces exercising forearm blood flow in humans
Why the study?
Does hyperbaric hyperoxia reduce exercising forearm blood flow in humans?
Population
7 subjects (6 men/1 woman; 25 ± 1 yr)
Comparison
Hyperbaric hyperoxia during forearm exercise vs Normoxia and hyperbaric normoxia during forearm…
Design
Other
Authors
Discussion
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Member takes
Implication
Hyperbaric hyperoxia may limit exercising muscle perfusion; leaves open relevance to performance or patient outcomes.
Structured PICO
Does hyperbaric hyperoxia reduce exercising forearm blood flow in humans?
P
Population
7 subjects (6 men/1 woman; 25 ± 1 yr)
I
Intervention
Hyperbaric hyperoxia (100% O2, 2.82 ATA, PiO2 ≈ 2,100 mmHg) during forearm exercise (20% of maximum)
C
Comparator
Normoxia (21% O2, 1 ATA, PiO2 ≈ 150 mmHg) and hyperbaric normoxia (7.4% O2, 2.82 ATA, PiO2 ≈ 150 mmHg) during forearm exercise
O
Outcome
Forearm blood flow (FBF) and Forearm vascular conductance (FVC)surrogate
Hyperbaric hyperoxia attenuates exercise hyperemia in skeletal muscle, indicating that blood flow regulation during exercise is highly dependent on oxygen availability.
Cite This Study
Casey et al. (2011) studied this question.