Key result
BMI and waist circumference show comparable moderate correlations with insulin resistance in nondiabetic South Asians.
Cross-Sectional (n=923)
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AIM: The aim of this study was to test the hypothesis that body mass index (BMI) and waist circumference (WC) associate to a comparable degree with insulin resistance and cardiometabolic risk factors in South Asians. METHODS: We measured blood pressure and fasting glucose, insulin, triglyceride, high-density lipoprotein cholesterol (HDL-C), high-sensitivity C-reactive protein (hs-CRP), and fibrinogen and calculated the homeostasis model assessment of insulin resistance (HOMA-IR) in a community-based sample of 923 nondiabetic South Asians. RESULTS: BMI and WC were highly correlated in both genders (r = 0.82 and 0.87). The relationship between BMI and values of blood pressure, glucose, insulin, HOMA-IR, triglyceride, HDL-C, hs-CRP, and fibrinogen was comparable to that between WC and these variables. Fasting insulin and HOMA-IR correlated most strongly with BMI (r = 0.49 to 0.56) and WC (r = 0.52 to 0.59). CONCLUSION: These results show that BMI and WC associate to a comparable degree with estimates of insulin resistance and related metabolic abnormalities in South Asians.
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Abbasi et al. (2012) conducted a cross-sectional in Insulin resistance and cardiometabolic risk in nondiabetic South Asians (n=923). Body mass index (BMI) vs. Waist circumference (WC) was evaluated on Fasting insulin, HOMA-IR, and cardiometabolic risk factors (blood pressure, glucose, triglyceride, HDL-C, hs-CRP, and fibrinogen) (r = 0.49 to 0.56 (BMI) vs r = 0.52 to 0.59 (WC)). BMI and waist circumference correlated comparably with fasting insulin and HOMA-IR (r=0.49-0.56 vs r=0.52-0.59) in nondiabetic South Asians.
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