Why the study?
Does body fat distribution influence hepatic and peripheral insulin sensitivity in obese premenopausal women?
Does body fat distribution influence hepatic and peripheral insulin sensitivity in obese premenopausal women?
Upper body fat localization in obese women is associated with greater hepatic and peripheral insulin resistance compared to lower body fat localization, potentially explaining higher rates of glucose intolerance.
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Upper body fat may flag higher insulin resistance risk in obese women; leaves open causal mechanisms and clinical utility.
Peiris et al. (1988) studied this question.
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