Why the study?
Does morbid obesity alter glucose uptake and blood flow in adipose tissue and muscle after a mixed meal in women?
Does morbid obesity alter glucose uptake and blood flow in adipose tissue and muscle after a mixed meal in women?
In morbidly obese women, insulin-stimulated glucose use and blood flow are impaired in muscle and adipose tissue, though increased total fat mass compensates for insulin resistance by acting as a glucose sink.
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Supports tissue-specific insulin resistance in morbid obesity; extends prior observations but leaves open clinical implications pending longitudinal data.
Mitrou et al. (2009) studied this question.
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