What question did this study set out to answer?

To evaluate acute and intermediate-term clinical outcomes and identify predictors of mortality among nonagenarian patients undergoing percutaneous coronary intervention.

December 1, 2009Clinical CardiologyOpen Access

Percutaneous Coronary Interventions in Nonagenarians: In‐Hospital Mortality and Outcome at One Year Follow‐up

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Why the study?

What are the acute and intermediate-term clinical outcomes and mortality rates of percutaneous coronary intervention in nonagenarian patients?

Population

32 consecutive nonagenarian patients undergoing percutaneous coronary intervention

Design

Cohort

Follow-up

1 year

Authors

RPRupen ParikhHunterdon Medical Center SCSrinivas ChennareddySeton Hall University VDVincent A. DeBariSt. Joseph’s University Medical Center

Discussion

Member takes

Implication

May support PCI consideration in selected nonagenarians; leaves open need for randomized trials on selection and comparative outcomes.

Key Points

To evaluate acute and intermediate-term clinical outcomes and identify predictors of mortality among nonagenarian patients undergoing percutaneous coronary intervention.
Analyzed 32 consecutive nonagenarian patients undergoing percutaneous coronary intervention between January 2001 and August 2006.
Identified baseline clinical presentations: ST-segment elevation myocardial infarction (n=6, 19%), non-STEMI (n=10, 31%), and unstable angina pectoris (n=16, 50%).
Applied receiver-operator characteristic curve analysis to evaluate mortality associations with blood pressure, heart rate, left ventricular ejection fraction, and serum creatinine.
Immediate procedural success was achieved in 28 of 32 patients (88%).
Cumulative mortality was 9% (n=3) at hospital discharge, 19% (n=6) at 6 months, and 19% (n=6) at 1-year follow-up.
Hypotension and reduced left ventricular ejection fraction correlated significantly with in-hospital mortality and adverse clinical outcomes.

Structured PICO

What are the acute and intermediate-term clinical outcomes and mortality rates of percutaneous coronary intervention in nonagenarian patients?

Population

32 consecutive nonagenarian patients undergoing percutaneous coronary intervention (19% STEMI, 31% NSTEMI, 50% unstable angina pectoris)

Intervention

Percutaneous coronary intervention (PCI)

Outcome

Acute and intermediate term clinical outcomes including in-hospital mortality, procedural success, and mortality at 1 year follow-uphard clinical

PCI in nonagenarians is associated with high procedural success and acceptable 1-year mortality, though hypotension and low ejection fraction predict worse outcomes.

Cite This Study

Parikh et al. (2009) studied this question.

synapsesocial.com/papers/6a79673602ab7a73dd0253eb https://doi.org/10.1002/clc.20596

Topics

Coronary artery disease

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Percutaneous Coronary Interventions in Nonagenarians: In‐Hospital Mortality and Outcome at One Year Follow‐up

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Percutaneous Coronary Interventions in Nonagenarians: In‐Hospital Mortality and Outcome at One Year Follow‐up

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider