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September 1, 1993Stroke

Suppressed sympathetic skin response in brain infarction.

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Why the study?

Does brain infarction alter sympathetic skin response compared to healthy controls?

Population

58 patients with brain infarction (49 hemispheral, 9 brain stem) and 36 healthy control subjects

Comparison

Brain infarction (acute and late phases) vs Healthy control subjects

Design

Case-control

Authors

JKJuha T. KorpelainenOulu University HospitalUTUolevi TolonenOulu University HospitalKSK. A. SotaniemiOulu University Hospital

Discussion

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Implication

Impaired sympathetic skin responses may reflect autonomic dysfunction post-stroke; leaves open prognostic or management utility.

Structured PICO

Does brain infarction alter sympathetic skin response compared to healthy controls?

P
Population
58 patients with brain infarction (49 hemispheral, 9 brain stem) and 36 healthy control subjects
I
Intervention
Brain infarction (acute and late phases)
C
Comparator
Healthy control subjects
O
Outcome
Sympathetic skin response (amplitude and latency) to electric and auditory stimulationssurrogate

Brain infarction is associated with impaired sympathetic skin responses, indicating significant suppression of sympathetic reflex activity.

Cite This Study

Korpelainen et al. (1993) studied this question.

synapsesocial.com/papers/6a796fcf02ab7a73dd0259dahttps://doi.org/10.1161/01.str.24.9.1389
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sympathetic Skin Response and R-R Interval Variation in Cerebral Infarctions2003
  2. 2Cardiovascular autonomic reflexes in brain infarction.1994 · 131 citations
  3. 3Sympathetic skin responses (SSRs) in monofocal brain lesions: topographical aspects of central sympathetic pathways1995 · 54 citations
  4. 4Evaluation of Autonomic Nervous System Functions in Post-Stroke Patients2002 · 34 citations
  5. 5A Preliminary Study on Sympathetic Skin Response in Acute Ischemic Cerebrovascular Disease2023 · 1 citations